Analysis of Pathogens and Drug Resistance in 380 Children with Vulvovaginitis

VernacularTitle:儿童外阴阴道炎380例病原学与耐药性分析
Author: Wenmin LU ; Xiaoying HU ; Ying YE ; Liuhui WANG
Publication Type:Journal Article
Keywords: Children; Vulvovaginitis; Pathogen; Drug sensitivity test; Drug resistance
From: China Pharmacy 2015;(23):3216-3219
CountryChina
Language:Chinese
Abstract: OBJECTIVE:To explore the characteristics of pathogens distribution of pediatric vulvovaginitis and drug resis-tance,and to provide reference for clinical drug use. METHODS:409 strains of positive routine bacteria and fungus culture were collected from 380 children with vulvovaginitis in 2014. The pathogens culture and drug sensitivity were recorded. RESULTS:The top 5 bacteria were Escherichia coli [36.67%(150/409)],Haemophilus influenzae [20.29%(83/409)],Streptococcus hemolyticus group A [13.20%(54/409)],Klebsiella pneumonia [8.80%(36/409)] and Staphylococcus aureus [5.37%(22/409)]. CONCLU-SIONS:The main pathogenic bacteria of pediatric vulvovaginitis is Gram negative bacilli,so that drug resistance should be paid at-tention to improve therapeutic efficacy when antibiotics are used in the clinic. The result of sensitivity test should be taken as basis for rational application of antibiotics in the treatment.