Anesthetic Effect of Dexmedetomidine in Pelvic Floor Reconstructive Surgery of Elderly Patients with Pelvic organ Prolapse
10.6039/j.issn.1001-0408.2015.33.06
- VernacularTitle:右美托咪定用于盆腔器官脱垂老年患者盆底重建术的麻醉效果
- Author:
Xiaohong LI
;
Hongmei YUAN
;
Shiqin XU
;
Fan XIA
;
Wangen WANG
;
Xiaofeng SHEN
- Publication Type:Journal Article
- Keywords:
Dexmedetomidine;
Elderly patients;
Pelvic floor reconstructive surgery
- From:
China Pharmacy
2015;26(33):4626-4628
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the anesthetic effect of dexmedetomidine in pelvic floor reconstructive surgery of elderly patients with pelvic organ prolapse(POP). METHODS:60 elderly patients with pelvic floor reconstructive surgery were randomly di-vided into observation group and control group. Observation group was treated with 0.5 μg/kg dexmedetomidine by pumping and control group was treated with 0.125 ml/kg 0.9% sodium chloride injection by pumping 15 min before anesthesia,and conventional intravenous induction was conducted after 15 min. MAP,HR and bispectral index(BIS)in entering the room(T0),5 min after ad-ministration(T1),immediate intubation(T2),1 min after intubation(T3),5 min after intubation(T4),surgical skin incision(T5), immediate extubation(T6)and 5 min after extubation(T7),restlessness score,sedation score,recovery time and incidence of ad-verse reactions in 2 groups were observed. RESULTS:MAP and HR in observation group in T1-7 were significantly lower than T0 and control group,MAP and HR in control group in T2-7 were significantly high than T0 except that T1 was significantly lower than T0,the differences were statistically significant(P<0.05);BIS in 2 groups T1-7 was significantly lower than T0,the differences were statistically significant(P<0.05),however,there was no significant difference between 2 groups(P>0.05). Restlessness score in observation group was significantly lower than control group,sedation score was significantly higher than control group,the differ-ence was statistically significant(P<0.05),there was no significant difference in the recovery time between 2 groups(P>0.05). There were no obvious adverse reactions in 2 groups during treatment. CONCLUSIONS:Dexmedetomidine can effectively reduce the stress response and maintain cycle stability in the treatment of elderly patients with pelvic floor reconstructive surgery,with good safety.
