Distribution of Risk Factors and Pathogens of Ventilator-associated Pneumonia in ICU and Drug Sensibility Analysis
10.6039/j.issn.1001-0408.2015.20.14
- VernacularTitle:重症监护室呼吸机相关性肺炎发生的危险因素和病原菌分布及药敏分析
- Author:
Xuemei CHEN
;
Ning YANG
- Publication Type:Journal Article
- Keywords:
Ventilator-associated pneumonia;
Risk factor;
Pathogen;
Drug resistance
- From:
China Pharmacy
2015;(20):2777-2779
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To analyze the risk factors,pathogens and drug sensitivity test of ventilator-associated pneumonia (VAP) in ICU. METHODS:A case-control study was conducted to analyze the clinical data of 190 patients receiving mechanical ventilatory support in ICU. RESULTS:The incidence of VAP in our hospital was 48.4%;elderly patients(>65 years),duration of mechanical ventilation(>5 d),use of corticosteroids,antacid drugs,indwelling stomach tube,and combined use of antibiotics were the risk factors of VAP;among the 162 pathogens,39 were Gram-positive bacteria(24.07%),102 were Gram-negative bacte-ria (62.96%),21 were fungi (12.96%);multi-drug resistance existed in most pathogens. CONCLUSIONS:A variety of factors are closely associated with the incidence of VAP;the main pathogens of VAP are Gram-negative bacteria;the phenomenon of multi-drug resistance is common. Some measures are adopted to decrease the incidence of VAP,such as strengthen monitoring of el-derly patients,to improve their immunity;use hormonal drugs reasonably;shorten the course of mechanical ventilation as much as possible,and plan ventilator removal;elevate the head of the bed and clean the oral for patients receiving gastric canal implantation and enteral nutrition;clean hands in accordance with asepsis principle strictly,and use antibacterials reasonalbly.
