Literature Analysis of 66 Cases of Drug-induced Hyperkalemia

VernacularTitle:66例药源性高钾血症文献分析
Author: Xiaolei REN ; Yiqiu ZHAN ; Chunyan ZHANG ; Haiying ZHANG ; Wanyu FENG
Publication Type:Journal Article
Keywords: Hyperkalemia; Adverse reaction; Drug safety
From: China Pharmacy 2015;(20):2790-2792
CountryChina
Language:Chinese
Abstract: OBJECTIVE:To investigate the characteristics and related factors of drug-induced hyperkalemia,present preven-tive measures and provide reference for the rational drug use. METHODS:46 literatures of individual cases and group cases of drug-induced hyperkalemia publicly reported in domestic medical journals from 1979 to 2014 were collected and analyzed statistical-ly,including 66 cases. RESULTS:66 cases with drug-induced hyperkalemia were mainly involved in cardiovascular drugs and im-munosuppressants. Most of them were improved after drug withdrawal and symptomatic treatment,and 2 cases died. CONCLU-SIONS:Drug-induced hyperkalemia are potentially dangerous. It is necessary to be vigilant,prevent and control timely and reduce the incidence of severe adverse reactions.