Clinical Observation of Shexiang Baoxin Pills in the Treatment of Coronary Heart Disease Patients with Chronic Heart Failure and Ventricular Premature Beat
10.6039/j.issn.1001-0408.2015.20.33
- VernacularTitle:麝香保心丸治疗冠心病合并慢性心力衰竭伴室性早搏的临床观察
- Author:
Hongxin ZHANG
- Publication Type:Journal Article
- Keywords:
Shexiang baoxin pills;
Shensong yangsin capsules;
Coronary heart disease;
Chronic heart failure;
Premature ven-tricular contractions
- From:
China Pharmacy
2015;(20):2832-2834
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To compare the clinical efficacy and safety of Shexiang baoxin pills and Shensong yangsin capsules in the treatment of coronary heart disease complicated with chronic heart failure and premature ventricular contractions. METHODS:129 patients with chronic heart failure and premature ventricular contractions were randomly divided into blank group(n=43),ob-servation group(n=43)and control group(n=43). All groups received routine treatment as oxygen inhalation,diuretics. Control group additionally received Shensong yangsin capsules 4 pills for 3 times per day. Observation group additionally received Shexiang baoxin pills 2 pills for 3 times per day. Treatment course of 2 groups lasted for 3 months. Clinical efficacies of 2 groups were ob-served,and heart function,cardiovascular autonomic nervous function and vascular endothelial function were observed before and after treatment. RESULTS:Total effective rate of observation group was significantly higher than that of control group(P<0.05). SDNN,SDANN,RMSSD,QTd was no statistical significance between control group and observation group(P>0.05). LVEF, NO of observation group were significantly higher than that of control group(P<0.05),IVST,LVDd,LVPWT,ET of observation group were significantly lower than that of control group(P<0.05). But control group and observation group were better than the blank group,and no obvious adverse reaction. CONCLUSIONS:Shexiang baoxin pills is more effective than Shensong yangsin cap-sules in the treatment of coronary heart disease complicated with chronic heart failure and premature ventricular contractions.
