Clinical significance of joint detection with cholyglycine and total bile acid intrahepafic cholestasis during pregnancy
10.3969/j.issn.1673-4130.2016.19.030
- VernacularTitle:血清肝胆酸及总胆汁酸联合检测在妊娠期肝内胆汁淤积症中的临床意义
- Author:
Yunyun XIE
;
Liquan LU
;
Peng WANG
- Publication Type:Journal Article
- Keywords:
cholyglycine;
total bile acid;
intrahepafic cholestasis during pregnancy
- From:
International Journal of Laboratory Medicine
2016;37(19):2734-2735
- CountryChina
- Language:Chinese
-
Abstract:
Objective To research the significance of detection of cholyglycine(CG) and total bile acid (TBA ) in intrahepatic cholestasis of pregnancy(ICP) .Methods Totally 85 gestational patients of ICP and 85 normal pregnancy pregnant women(control group) were chosen .Indexes including CG ,TBA ,ALT ,AST and TBIL were detected ,and the results were compared .Results In ICP group ,the levels of serum CG ,TBA ,ALT ,AST and TBIL were significantly higher than those in the normal control group ,and the differences were statistically significant(P< 0 .05) ;The positive rates of serum CG and TBA in ICP were significant higher than those in control group(P< 0 .05) .Conclusion The level of CG and TBA in intrahepatie cholestasis of pregnancy are significantly increased and might be sensitive indicators of gestaional diabetes in intrahepatie cholestasis of pregnancy ,the joint detection is of great clinical significance for ICP early diagnosis and monitoring .
