Effect of anticoagulation combined with hypolipidemic in treatment of diabetic atherosclerosis
10.3969/j.issn.1005-1678.2016.08.032
- VernacularTitle:抗凝联合降血脂治疗糖尿病动脉粥样硬化的疗效观察
- Author:
Min WEN
;
Limin ZHAO
;
Songfang LIU
- Publication Type:Journal Article
- Keywords:
diabetes mellitus;
atherosclerosis;
aspirin enteric-coated tablets;
atorvastatin;
clinical curative effect
- From:
Chinese Journal of Biochemical Pharmaceutics
2016;36(8):116-118
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of aspirin combined with atorvastatin in the treatment of diabetic atherosclerosis.Methods 120 patients with diabetic atherosclerosis form August 2014 to February 2016 were selected,and randomly divided into treatment group and control group,60 cases in each group.Control group treated with aspirin enteric-coated tablets,the treatment group treated with aspirin enteric-coated tablets combined with atorvastatin,comparing the two groups before and after treatment of fasting blood glucose,blood lipid related index,carotid intima-media thickness and plaque thickness,and the adverse reactions.Results After treatment, the levels of fasting blood glucose and fasting insulin in treatment group were significantly lower than control group(P<0.05),the carotid intima-media thickness and plaque thickness in treatment group was significantly lower than control group(P<0.05).The levels of TG,TC,LDL-C and HDL-C in treatment group were significantly improved(P <0.05).Conclusion Aspirin enteric coated tablets combined with atorvastatin efficacy significantly in the treatment of diabetic atherosclerosis.
