The status and progress of lamellar hole-associated epiretinal proliferation
10.3760/cma.j.issn.1005-1015.2016.05.027
- VernacularTitle:黄斑板层裂孔相关视网膜前增生的研究现状与进展
- Author:
Xin LI
;
Qi ZHANG
;
Peiquan ZHAO
- Publication Type:Journal Article
- Keywords:
Retinal perforations;
Macula lutea;
Membranes;
Review
- From:
Chinese Journal of Ocular Fundus Diseases
2016;32(5):547-549
- CountryChina
- Language:Chinese
-
Abstract:
Recently,the new term lamellar hole-associated epiretinal proliferation was introduced to describe a specific epiretinal proliferation.Different from conventional epimacular retinal membrane,lamellar hole-associated epiretinal proliferation (LHEP) can be found around the edge of lamellar macular holes and part of full thickness macular holes.It is defined as a thick homogenous layer of yellowish material without any contractive properties on the epiretinal surface with medium reflectivity on optical coherence tomography images.Immunocytochemical analysis showed the presence of glial cells,fibroblasts,hyalocytes and collagen type Ⅱ.Electron microscopy revealed fibroblasts and hyalocytes as predominant cell types,densely packed in cell agglomerations.LHEP is a secondary event in lamellar macular hole formation and may represent a repair process after large and deep retinal defect.Further studies on its clinical features and clinical significance are still required.
