The research progress of gene mutations in children with Wilms tumor
10.3760/cma.j.issn.1673-4408.2016.10.008
- VernacularTitle:儿童肾母细胞瘤基因突变的研究进展
- Author:
Rui XU
- Publication Type:Journal Article
- Keywords:
Nephroblastoma;
Children;
Gene mutation
- From:
International Journal of Pediatrics
2016;43(10):774-777
- CountryChina
- Language:Chinese
-
Abstract:
Nephroblastoma is the most common pediatric renal tumor.The research progress of gene mutations in Wilms tumor children is reviewed in this paper.The WT1 gene,CTNNB1 gene and WTX gene plays a role in onset of Wilms tumor,and the MYCN gene,P53 gene and SIX1 gene may be associated with the prognosis.