Analysis of Perioperative Application of Antibiotics in GynecologicalⅡandⅢIncision Surgery of Our Hospital before and after Special Rectification
10.6039/j.issn.1001-0408.2015.29.05
- VernacularTitle:专项整治前后我院妇科Ⅱ、Ⅲ类切口围术期抗菌药物应用分析
- Author:
Jun LIU
;
Laicheng WANG
;
Hui WANG
- Publication Type:Journal Article
- Keywords:
Gynecological surgery;
Perioperative period;
Antibiotics;
Rational drug use
- From:
China Pharmacy
2015;(29):4045-4047
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To provide reference for perioperative rational application of antibiotics in gynecologicalⅡandⅢinci-sion surgery. METHODS:The perioperative patients of typeⅡandⅢincision surgery were collected from our hospital during Jul.-Dec. 2013-Jul.-Dec.2014,and then divided into pre-rectification group and post-rectification group. The prophylactic application of antibiotics in 2 groups were analyzed statistically. RESULTS:After rectification,rational rate of prophylactic medication in-creased from 5.38% to 89.69%(P<0.01);rational rate of prophylactic medication time increased from 11.83% to 91.75%(P<0.01);prophylactic medication duration decreased from (12 ± 2.1)d to(5.5 ± 1.9)d(P<0.01);after rectification,both total drug cost and drug cost per capita decreased significantly (P<0.01);postoperative infection rate showed no significant change before and after rectification (P>0.05). After rectification,usage and dosage of β-lactam antibiotics were in line with pharmacokinetics, Intravenous drip was adjusted from once a day to twice a day,and its rational rate increased significantly compared to before rectifi-cation(P<0.05). CONCLUSIONS:The antibiotics special rectification activities significantly promote the rationality of periopera-tive prophylactic application of antibiotics in gynaecologyⅡandⅢincision surgery of our hospital,reduce adverse drug reactions and resistant strains due to irrational use of drugs,and decrease the drug cost.
