Investigation and Analysis of Drug Information for the Elderly in Package Insert of Common Oral Antihyper-tensive Drugs in Our Hospital
10.6039/j.issn.1001-0408.2015.29.43
- VernacularTitle:我院常用口服抗高血压药说明书中老年人用药信息的调查分析
- Author:
Jing ZHANG
;
Yuancheng CHEN
- Publication Type:Journal Article
- Keywords:
Antihypertensive drugs;
Package inserts;
Drug use for the elderly
- From:
China Pharmacy
2015;(29):4153-4155
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To ensure the safety of the elderly medication. METHODS:The package inserts of 38 kinds of com-mon oral antihypertensive drugs were collected from our hospital,and analyzed statistically in respects of drug information for the elderly in package inserts of domestic and foreign drugs and those of antihypertensive drugs. RESULTS:In 21 package inserts (55.26%),there were specific dosage for elderly;in 16(42.10%),there were certain matters needing attention in“drug use for the elderly”;in 15,the marked rate of“pharmacokinetics study for the elderly”was 39.47%.Except for ARB antihypertensive drugs, related drug information was hardly labeled in package inserts of other types. The label of“starting at low dose”accounted for 21.05%;the label of“no need to adjust dose,“use drug carefully”,“no age differences”accounted for 15.79%,15.79% and 13.16%,respectively. The label rates of other items were in low level. The drug package inserts at home were lack of information of drug use for the elderly,compare to abroad. CONCLUSIONS:There are some problems in package inserts of common oral anti-hypertensive drugs,such as usage and dosage,matters need attention,pharmacokinetics,poor description in details. Drug informa-tion for the elderly in the package inserts of antihypertensive drug needs to be more detailed;the drug regulatory agency and the drug manufactures should make joint efforts to let drug package inserts more detailed about drug use for the elderly to ensure medi-cation safety.
