In vitro biological screening of the stem of Desmodium elegans
10.1016/S2221-1691(13)60143-4
- Author:
Arshad KHAN
;
Rabia USMAN
;
Mingliang WANG
;
Abdur RAUF
;
Naveed MUHAMMAD
;
Akhatar AMAN
- Publication Type:Journal Article
- Keywords:
Leguminosae;
Desmodium elegans;
Brine shrimp cytotoxicity;
Phytotoxic;
Insecticidal and antimicrobial activities
- From:Asian Pacific Journal of Tropical Biomedicine
2013;(9):711-715
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the medicinal importance of the stem of Desmodium elegans, methanolic extract, and its different solvent fractions were evaluated for brine shrimp lethality, insecticidal and phytotoxicity, antifungal, and antibacterial activities.
Methods:The methanolic extract and its solvent fractions were tested for cytotoxic, phytotoxic, insecticidal, antifungal, and antibacterial effects using our previous published protocols.
Results:The methanolic, DCM, ethyl acetate and n-butanol fractions exhibited insecticidal effect against Callosobruchus analis and Rhyzopertha dominic. The methanolic extract, n-hexane, DCM ethyl acetate and n-butanol showed 75, 85, 85, 65 and 5%phytotoxicity at the tested concentration of 500μg/mL respectively. The solvent fractions (DCM and ethyl acetate) were effective against F. solani (10%and 20%inhibition respectively). All the tested samples were devoid of cytotoxic and antibacterial effects.
Conclusions:It was concluded that this plant can be practiced for control of weeds and insects.
