Identification of active pocket and protein druggability within envelope glycoprotein GP2 from Ebola virus
- Author:
Beuy JOOB
;
Viroj WIWANITKIT
- Publication Type:Journal Article
- Keywords:
Active pocket;
Ebola virus;
Druggability;
Envelope glycoprotein GP2
- From:Asian Pacific Journal of Tropical Biomedicine
2014;(12):939-940
- CountryChina
- Language:Chinese
-
Abstract:
The drug searching for combating the present outbreak of Ebola virus infection is the urgent activity at present. Finding the new effective drug at present must base on the molecular analysis of the pathogenic virus. The in-depth analysis of the viral protein to find the binding site, active pocket is needed. Here, the authors analyzed the envelope glycoprotein GP2 from Ebola virus. Identification of active pocket and protein druggability within envelope glycoprotein GP2 from Ebola virus was done. According to this assessment, 7 active pockets with varied druggability could be identified.
