Antifungal activity of four honeys of different types from Algeria against pathogenic yeast:Candida albicans and Rhodotorula sp.
10.1016/S2221-1691(12)60096-3
- Author:
Ahmed MOUSSA
;
Djebli NOUREDDINE
;
Aissat SAAD
;
Meslem ABDELMELEK
;
Benhalima ABDELKADER
- Publication Type:Journal Article
- Keywords:
Honey;
Antifungal activity;
Candida albicans;
Rhodotorula sp
- From:Asian Pacific Journal of Tropical Biomedicine
2012;(7):554-557
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the antifungal activity of four honeys of different types from Algeria against pathogenic yeast i.e. Candida albicans (C. albicans) and Rhodotorula sp. Methods:Four Algeria honeys of different botanical origin were analyzed to test antifungal effect against C. albicans, and Rhodotorula sp. Different concentrations (undiluted, 10%, 30%, 50%and 70%w/v) of honey were studied in vitro for their antifugal activity using C. albicans and Rhodotorula sp. as fungal strains. Results:The range of the diameter of zone of inhibition of various concentrations of tested honeys was (7-23 mm) for Rhodotorula sp., while C. albicans showed clearly resistance towards all concentrations used. The MICs of tested honey concentrations against C. albicans and Rhodotorula sp. were (70.09-93.48)%and (4.90-99.70)%v/v, respectively. Conclusions:This study demonstrates that, in vitro, these natural products have clearly an antifungal activity against Rhodotorula sp. and C. albicans.