Genetic Polymorphism of Nine Non-CODIS STR Loci in Hu-nan Province-based Chinese Han Population
10.3969/j.issn.1004-5619.2014.06.010
- Author:
Juanjuan GUO
;
Ying LIU
;
Yadong GUO
;
Jie YAN
;
Yunfeng CHANG
;
Jifeng CAI
;
Ting LU
;
Lagabaiyila ZHA
- Publication Type:Journal Article
- Keywords:
forensic genetics;
polym orphism,genetic;
short tandem repeats;
non-CODIS;
Han nationality;
Hunan
- From:Journal of Forensic Medicine
2014;(6):441-445
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the allelic frequency distribution and genetic parameters of nine non-CODIS DNA index systems of the short tandemrepeat (STR ) loci (D2S1772, D6S1043, D7S3048, D8S1132, D11S2368, D12S391, D13S325, D18S1364, and GATA198B05). Methods A total of 353 blood samples were collected, extracted, amplified, and analyzed fromunrelated healthy individuals of Han na-tionality in Hunan Province, China. Results O ne hundred and fourteen alleles were observed in the pop-ulation with corresponding allelic frequencies ranged from0.001 0 to 0.323 0. For all the nine non-CODIS STR loci, the observed genotypic data showed no significant deviations fromthe Hardy-W einberg equi-librium. The Ho, He, PIC, D P, and PE of the studied non-CODIS STR loci ranged from0.108 0 to 0.195 0, 0.805 0 to 0.892 0, 0.770 0 to 0.860 0, 0.925 0 to 0.966 0 and 0.607 0 to 0.780 0, respectively. Conclusion N ine non-CODIS STR loci have high degrees of polymorphisms, which may be useful in in-dividual forensic identification and parentage testing in forensic practice.
