Expression and Mechanism of αB-crystallin in Retina and Extraocular Tissues and Organs
10.3969/j.issn.1004-5619.2014.06.017
- VernacularTitle:αB晶状体蛋白在视网膜及眼外组织器官中表达及其作用机制
- Author:
Dongmei LIU
;
Shu ZHOU
;
Jiemin CHEN
;
Shuya PENG
;
Wentao XIA
- Publication Type:Journal Article
- Keywords:
forensic m edicine;
α-crystallin B chain;
review [publication type];
retina
- From:
Journal of Forensic Medicine
2014;(6):470-473
- CountryChina
- Language:Chinese
-
Abstract:
αB-crystallin is the structural protein of vertebrate lens, w hich is w idely expressed in non-lens tissue. As one of the heat shock protein fam ily m em bers,αB-crystallin possesses biological proper-ties of m olecular chaperones and anti-apoptotic effects. Multi-factor injuries, such as retinopathy, inflam-m ation and nervous system diseases, have a closely relationship w ith αB-crystallin. T his paper review s the research progress of the expression and m echanism ofαB-crystallin in retina and extraocular tissues and organs.