Analysis of Pesticides in Blood Specimen by GC/MS with Accelerated Solvent Ex-traction
10.3969/j.issn.1004-5619.2014.06.015
- VernacularTitle:快速溶剂萃取-气相色谱-质谱联用法分析血液中的农药
- Author:
Wenhai LI
;
Dawei LIN
;
Honglei SUN
;
Maimaitituxun MUTAILIFU
;
Lei WANG
- Publication Type:Journal Article
- Keywords:
forensic toxicology;
gas chrom atography-m ass spectrom etry;
accelerated solvent extraction;
pesticides;
blood
- From:Journal of Forensic Medicine
2014;(6):463-465
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develop the accelerated solvent extraction (ASE ) for determ ining pesticides pre-sent in blood sam ples. Methods Pesticides were extracted by ASE with optimized param eters to study recovery rate affected by extraction tem perature, time and agent. GC/MS was used to perform quantita-tive analysis.Results The recovery rates of eight pesticides were 70.6%-92.4%. The coefficient of variation was less than 5.0%. Agood linear relationship was obtained at the concentration range of 0.5-5.0μg/m L . Conclusion The m ethod was fast and sim ple with high recovery rate and good repeatability. It can be applied to analyze pesticides present in the blood specimen.
