On the safety of oral cholerae vaccine produced at Company No1 of Vaccine and Biological Preparation
- Author:
Doan Thi Thuy
- Publication Type:Journal Article
- Keywords:
oral cholera vaccine
- MeSH:
Cholera Vaccines;
Cholera;
Biological Products
- From:Journal of Practical Medicine
2003;445(3):44-45
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
During 2001-2002 period, 19 lots of oral cholera vaccines were prepared at the Company No1 of Vaccine and Biological Preparation. Weight gain tests were performed on white mice, each test used 20 mices for vaccine sample and 20 mices for control. According to WHO standards and Central National of Control for Biological Preparation standards, cholera vaccine does not cause death for mice, and mean weight of mouse after three days injection is at least equal to that of infection moment and the mean weight gain of the seventh day is higher or equal 60% of control. All 19 lots of vaccine had had high safety