Photoacoustic Tomography for Micro-blood Vessel
10.3969/j.issn.1005-202X.2010.01.026
- VernacularTitle:模拟微血管的光声成像技术研究
- Author:
Tao LU
;
Huiyong MAO
- Publication Type:Journal Article
- Keywords:
biomedical optics;
photoacoustic tomography;
unfocused ultrasound transducer;
tissue-mimicking phantom
- From:
Chinese Journal of Medical Physics
2010;27(1):1665-1667
- CountryChina
- Language:Chinese
-
Abstract:
Objectieve:In order to get the photoacoustic (PA) image of micro-blood vessel deep inside biological tissue.Materials and Methods:A 532nm pulse laser with the repetition rate of 10Hz was used as the pumping source.A wide band unfocused needle ultrasound transducer was used to collect time-domain PA signal of the tissue-mimicking phantom by circular scan.The 2D optical absorption image was reconstructed by time-domain spherical back projection algorithm.The spatial resolution was measured by line-spread-function(LSF).Results:The experimental results demonstrated that the spatial resolution was 0.1 mm and the PA image of the micro-vascular network agreed well with the tissue-mimicking phantom.Conclusion:The proposed method is valuable for the diagnosis of early cancer inside tissue.
