Therapeutic evaluation of methotrexate combined with hysteroscope for treatment of cervix pregnancy

VernacularTitle:甲氨蝶呤联合宫腔镜治疗宫颈妊娠疗效评价
Author: Hongjie YANG
Publication Type:Journal Article
Keywords: cervical pregnancy; methotrexate; mifepristone; hysteroscopy; treatment
From: Journal of Regional Anatomy and Operative Surgery 2014;(1):64-65
CountryChina
Language:Chinese
Abstract: Objective To explore the efficacy and safety of methotrexate combined with hysteroscopic in treatment of cervical pregnan-cy. Methods The data of 14 patients with cervical pregnancy were analyzed retrospectively. Results All patients were given combination therapy of mifepristone and methotrexate firstly,and they were discharged after bloodβ-HCG logarithmically decreased for further observation. Hysteroscopic surgery were applied whenβ-HCG level decreased to 100 mIU/mL. Conservative treatment received success in all 14 cases. It required 14~35 days,averagely (26. 5 ± 2. 7) days, methotrexate dosage of 50~150 mg,averagely (75. 5 ± 15. 0) mg, and mifepristone of volume 150~450 mg,averagely (275. 0 ± 54. 5) mg to make the bloodβ-HCG level decreased to 100 mIU/mL. The bleeding volume during hysteroscopy surgery was 5~50 mL,an average of (35. 6 ± 5. 2)mL. Conclusion Methotrexate combined with hysteroscopy is safe and fea-sible for treatment of cervical pregnancy.