Effect of form-deprivation myopia/amblyopia on mouse hyperglycemia retinal damage
10.11659/jjssx.1672-5042.201406013
- VernacularTitle:形觉剥夺性近视/弱视对小鼠高血糖视网膜微血管病变影响的形态学观察
- Author:
Hengdi ZHANG
;
Yi WANG
- Publication Type:Journal Article
- Keywords:
form-deprivation myopia/amblyopia;
hyperglycemia;
pericytes
- From:
Journal of Regional Anatomy and Operative Surgery
2014;(6):607-609
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe whether form-deprivation myopia/amblyopia could protect retinal microvascular system and postpone the development of diabetic retinopathy. Methods The form-deprivation myopia/amblyopia was established combined with hyperglycemia mouse model,and the retinal vascular endothelial cells and pericytes were counted. Results Endothelial cells/ pericytes ratio in hyperglyce-mia group is significantly lower than that in normal group and form-deprivation myopia/amblyopia combined with hyperglycemia group. Con-clusion Form-deprivation myopia/amblyopia combined with hyperglycemia mice have more pericytes than hyperglycemia mice.
