Expressions of Connexin43 and E-cadherin and their significance in invasive ductal carcinoma

VernacularTitle:乳腺浸润性导管癌连接蛋白43和上皮性钙黏蛋白相关性研究
Author: Yongjiu TU ; Yijing GAO ; Zhan CHEN ; Rui LI
Publication Type:Journal Article
Keywords: breast cancer; Connexin43; E-cadherin; correlation
From: Journal of Regional Anatomy and Operative Surgery 2014;(6):586-588
CountryChina
Language:Chinese
Abstract: Objective To explore the correlation of Connexion43(Cx43),E-cadherin(E-cad)in breast infiltrating ductal carcinoma tis-sue. Methods The expressions of Cx43 and E-cad proteins were detected in 89 cases breast infiltrating ductal carcinoma tissue,48 cases partition groups. by immunohistochemistry Elivision method. Results The expressions of Cx43 and E-cad has a better consistency in the tumor area,the border area and far cancer area of breast infiltrating ductal carcinoma. For both the negative expression in tumor area same time,the rate of lymph node metastasis was highest. Conclusion Cx43 and E-cad in breast invasive ductal carcinoma has a certain synergy in the process of the occurrence and development,which related to its metastasis occurred.