Correlations between obesity and arterial stiffness among population of different glucose tolerance status
10.11659/jjssx.1672-5042.201405019
- VernacularTitle:不同糖代谢状态人群的肥胖指标与动脉硬化的相关性
- Author:
Yimei CHEN
;
Jingtao DOU
;
Wenhua YAN
;
Liguang DONG
;
Yanhua LIAO
;
Shuyu WANG
;
Juming LU
;
Yiming MU
- Publication Type:Journal Article
- Keywords:
arterial stiffness;
obesity;
diabetes;
glucose tolerance status
- From:
Journal of Regional Anatomy and Operative Surgery
2014;(5):502-505
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the relationship between obesity and arterial stiffness among population of different glucose tolerance status. Methods A cross-sectional study recruited the population aged 40 years or older from ShiJingShan district in Beijing. 9080 subjects were included by measured weight, waist circumference (WC), body mass index (BMI), waist/hip ratio (WHR) and WC/height ratio (WHtR) and hemodynamic indexes and the aortic stiffness (using brachial-ankle pulse wave velocity(baPWV). They were divided into 3 groups based on the results of OGTT and diabetes history: normal glucose tolerance group ( NGT group) ,impaired glucose regulation group ( IGR group) and diabetes mellitus group ( DM group) . The association between baPWV and different obese indexes was analyzed by multi-ple linear regression. Results According to the criterion of WC, WHR and WHtR, baPWV of central obesity group was significantly higher than the normal group(P<0. 01). There was no statistically significant differences based on BMI in DM group(P>0. 05), but it was of sta-tistically significant differences in NGT group and IGR group. Central obese indexes( WC、WHR、WHtR) showed a positive correlation to PWV in the studied groups(P<0. 05). BMI was only positively correlated with baPWV in NGT group, there was no significant correlation in IGR and DM group(P>0. 05). After adjusting for age, gender and cardiovascular risk factors, the multiple regression analysis found that for every 0. 1 point increase in WHR and WHtR, the PWV increased 40. 6 cm/s and 55. 3cm/s respectively. Conclusion There is a positive correlation between central obese indexes (WC、WHR、WHtR) and arterial stiffness, and the central obese indexes correlated with arterial stiffness better than BMI.
