Relevant research on expression of C5b-9 and disease in gastric adenocarcinoma
10.11659/jjssx.03E016034
- VernacularTitle:C5b-9在胃腺癌中表达与疾病的相关性研究
- Author:
Dan TAN
;
Xiaoqin ZENG
- Publication Type:Journal Article
- Keywords:
gastric carcinoma complement;
C5b-9;
clinical stages
- From:
Journal of Regional Anatomy and Operative Surgery
2016;25(9):632-635
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the correlation between the expression of C5b-9 and the gastric carcinoma.Methods In this study, the human gastric adenocarcinoma (HGAC)tissues (n =32 cases)from 32 patients were evaluated by immunohistochemistry and tissue chip.The result was analyzed and evaluated by Multinomial logistic regression and likelihood ratio.Results Multinomial logistic regression and likelihood ratio testing showed that over-expression of C5b-9 in HGAC tissue was significantly correlated with clinical stage (P =0.007) and tumor stage (P =0.005),but not with tumor metastasis,lymphoid nodal status,sex or age.Conclusion C5b-9 can be the criteria of di-agnosis and clinical staging for gastric adenocarcinoma,which may help in diagnosis and assessment disease severity of human gastric carcinoma.
