Chemical and Pharmacological Researches on Hyoscyamus niger
10.3969/j.issn.1674-6384.2011.02.006
- Author:
Jun LI
;
Ji SHI
;
Xinwen YU
;
Jingkuan SUN
;
Qiming MEN
;
Tingguo KANG
- Publication Type:Journal Article
- Keywords:
alkaloids;
coumarinolignans;
flavonoids;
Hyoscyamus niger;
lignans;
saponins
- From:
Chinese Herbal Medicines
2011;03(2):117-126
- CountryChina
- Language:Chinese
-
Abstract:
The reports on chemical constituents of Hyoscyamus niger were summarized. The compounds include alkaloids, saponins, lignans, coumarinolignans, flavonoids, and some other nonalkaloidal compounds. TLC, HPLC, and GC were used for the qualitative and quantitative analyses of some chemical constituents in H. niger. Modern pharmacological experiments showed that H. niger had the analgesic, anti-inflammatory, antipyretic, anticonvulsant, spasmolytic, antidiarrhoeal, antisecretory, bronchodilatory, urinary bladder relaxant, hypotensive, cardiosuppressant, vasodilator, antitumor, and feeding deterrent properties. In addition, the toxicities of this medicinal plant were also described.