An Overview on the Progress of Chemical Constituents and Bioactivities of Plants in Urticaceae during 2000-2010
10.3969/j.issn.1674-6384.2011.01.004
- Author:
Jian WANG
;
Hongxing YANG
;
Yongzhen TENG
;
Pei YUAN
;
Rui TIAN
;
Chunbi LIAO
- Publication Type:Journal Article
- Keywords:
bioactivities;
chemical constituents;
nettle;
Urtica L.;
Urticaceae
- From:
Chinese Herbal Medicines
2011;03(1):9-16
- CountryChina
- Language:Chinese
-
Abstract:
Utticaceae includes about 1300 species in 47 genera which largely spread in wet tropical regions,and 341 species in 25 genera are in China.Some species are used in Chinese folk medicine.So far,studies on chemistry and pharmacology of Urticaceous plants are mainly focused on nettle of Urtica L.In this review,the chemical researches on 35 new compounds and related pharmacological effects of the plants in Urticaceae reported during2000-2010 are described.The 35 new compounds belong to the classes of lignan,secolignan,norlignan,flavonoid,alkaloid,sesquiterpenoid,triterpenoid,sterol,and sphingolipid.The main bioactivities include cytotoxic,antitumor,antimicrobial,antifungal,anti-BPH,anti-HIV,antidiabetic,hypolipidemic,5α-reductase inhibitory,hair regrowth promotion,and anti-oxidative activities.