In vitro prevention of chick pancreatic lipase activity by Abroma augusta extract
10.1016/S2221-1691(12)60301-3
- Author:
Nidhi GUPTA
;
Aditya GANESHPURKAR
;
Nishikant JATAV
;
Divya BANSAL
;
Nazneen DUBEY
- Publication Type:Journal Article
- Keywords:
Abroma augusta;
Anti-lipase;
Alkaloids;
Flavonoids
- From:Asian Pacific Journal of Tropical Biomedicine
2012;(z2):712-715
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate chick pancreatic lipase inhibitory activities of the Abroma augusta (A. augusta). Methods: A. augusta was first extracted with methanol and subjected to phytochemical screenings. Quantitative estimation of flavonoids, phenolics and alkaloids was done. Pancreatic lipase from chick pancreas was isolated and used as substrate for anti-lipase studies. Results:A. augusta extract effectively inhibited concentration dependent lipase activity, whereby extract at concentration 100 μg/mL inhibited 88.6% enzyme activity. Conclusions: From these results, it could be concluded that A. augusta can be used as a potential source anti-lipase agents.
