EXPRESSION OF YB-1 IN ENDOMETRIOSIS
10.3969/j.issn.1671-332X.2015.03.009
- VernacularTitle:YB －1在子宫内膜异位症中的表达
- Author:
Xiaolan LAI
;
Xing HUA
;
Bijun LIN
- Publication Type:Journal Article
- Keywords:
YB-1;
Endometriosis;
Serum;
Endometrium;
Expression
- From:Modern Hospital
2015;(3):33-35
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression and significance of YB -1 in serum and endometrial tis-sues in patients with endometriosis ( EMs ) for taking YB -1 EMs as an index of early diagnosis and treatment . Methods ELISAwas adopted to detect YB -1 expressions in serum of EMs group and control group .The expression of YB-1 in endometrial tissue in the EMs group and control group was detected by immunohistochemistry SP method . Results The average concentration of YB -1 in serum of EMs group (14.65 ±3.91 ug/L) was higherthan thatin the control group (9.64 ±2.37 ug/L), with statistically significant differences (p<0.05).The results of immuno-histochemistry showed that the expression of YB -1 was moderately positive in endometria of patients with EMs . Weakly positive expressions of YB -1 were detected in a fewcases of the control group .There are significant differ-ences in the positive expression rates of YB -1 between two groups ( p <0.05).Conclusion The expression of YB-1 in serum and endometria of patients with EMs is higher .YB-1 can not only be an intracellular marker , but also expected to become an ideal serological marker .
