THE EFFECT OF DIFFERENT CONCENTRATIONS OF HYPERTONIC SALINE FOR CERE-BRAL EDEMA ON BLOOD BIOCHEMICAL AND OSMOTIC PRESSURE
10.3969/j.issn.1671-332X.2015.06.003
- VernacularTitle:不同浓度高渗盐水对脑水肿患者血生化及渗透压的影响
- Author:
Yun XIAO
;
Zeliang TAN
- Publication Type:Journal Article
- Keywords:
Hypertonic saline;
Cerebral edema;
Blood biochemical;
Osmotic pressure
- From:
Modern Hospital
2015;(6):5-7
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of different concentrations of hypertonic saline for cerebral ede -ma on blood biochemical and osmotic pressure .Methods 60 cases were randomly divided into the 3% HS group, 7.5%HS group and the mannitol group .The patients were randomly assigned to infusion of 3% HS, 7.5% HS or 20%mannitol (all 2 mL/kg).Blood biochemical and osmotic pressure on patients were measured before and after the treatment among groups .Results Serum Na +, Cl -and osmotic pressure were significantly higher at 2 hours and 22 hours of reperfusion than at baseline (p<0.05) in the 7.5% HS group and the mannitol group .The difference were significant on serum Na +, Cl-and osmotic pressure at 2 hours and 22 hours of reperfusion in the 7.5% HS group and the mannitol group than in the 3% HS group(p<0.05).Conclusion 3% hypertonic saline had less effects on blood biochemical and osmotic pressure than other groups for patients of cerebral edema .It is worthy of popularization and application .
