SUBCUTANEOUS INJECTION OF FIXED-DOSE WEIGHT ADJUSTED UNFRACTIONATED HEPARIN TO PREVENT DEEP VENOUS THROMBOSIS AFTER HIP OPERATION
10.3969/j.issn.1671-332X.2009.08.016
- VernacularTitle:皮下注射固定剂量普通肝素预防髋部手术后下肢深静脉血栓形成
- Author:
Haizhou HUANG
- Publication Type:Journal Article
- Keywords:
UFH;
Hype hyodermic;
Fixed dosage;
LMWH;
Hip surgery;
DVT
- From:Modern Hospital
2009;9(8):33-35
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate safety and efficacy of fixed-dose weight adjusted unfractionated heparin to prevent deep venous thrombosis (DVT) after hip operation.Methods 56 patients were randomly divided into control group and experimental group.27 cases in control group were treated with subcutaneous low-molecular heparin, while 29 cases in experimental group treated with subcutaneous unfractionated heparin, and both were given twice daily 12 to 24 hours after operation for 7 days.The daily doses were adjusted to patients’ weight.The volume of blood transfused and postoperative blood loss was recorded, and levels of hemoglobin, platelet, prothrombin time and APTT were tested.Incidences of DVT were obtained.Results There was no significant difference in the volume of blood transfused and postoperative blood loss between two groups (p>0.05).There was no significant change of hemoglobin, platelet, prothrombin time and APTT on the first and seventh day after surgery (p>0.05).There was no significant difference in incidences of DVT in two groups (p>0.05).Conclusion Subcutaneous unfractionated heparin can effectively reduce the incidence of DVT after hip operation, and has a good result in treating DVT with low incidence of side effects.
