OPTIMIZATION OF EXTRACTION PROCESS OF SIMIAOYONGAN DECOCTION BY OR-THOGONAL TEST
10.3969/j.issn.1671-332X.2014.08.034
- VernacularTitle:正交设计法优选四妙勇安汤提取工艺
- Author:
Lin MA
;
Yongshu LIANG
;
Qi DUAN
- Publication Type:Journal Article
- Keywords:
Simiaoyongan decoction;
Extracting technology;
Orthogonal Test;
Chlorogenic acid;
Harpagoside
- From:
Modern Hospital
2014;(8):82-84
- CountryChina
- Language:Chinese
-
Abstract:
Objective To research the best extracting technology of simiaoyongan decoction.Methods As the total contents of chlorogenic acid and harpagoside to be evaluation indicator, adopted L9 (34 ) orthogonal design to select out the best extraction.The main determination was by HPLC method.Results Accounted by the total contents of the two composi-tions, the influential effects of the experimental results were extraction solvent >reflux times >the volume of extraction>the circumfluence time.Conclusion The best extracting technology is adding 10-fold times of 50% alcohol, percolating 1 hours, and three times.
