The research progress of amniotic fluid-derived mesenchymal stem cells in cancer therapy
10.3969/j.issn.1002-3070.2014.03.013
- VernacularTitle:羊水间充质干细胞在肿瘤治疗中的研究进展
- Author:
Dejun WANG
;
Guangmei ZHANG
- Publication Type:Journal Article
- Keywords:
Amniotic fluid-derived mesenchymal stem cells;
Cancer;
Therapy
- From:
Practical Oncology Journal
2014;(3):255-257
- CountryChina
- Language:Chinese
-
Abstract:
Amniotic fluid-derived mesenchymal stem cells(AF-MSCs)are multipotential,nonhemato-poietic progenitor cells that have an inherent ability to self -renew and to differentiate into many cell types ,inclu-ding osteoblasts,chondrocytes and adipocytes.Despite their high proliferation rate,no in vivo tumorigenicity has been reported and their karyotype was normal even after extensive expansion in culture .Several studies have dem-onstrated the inherent tumortropic properties of MSCs and their successful use as cellular vehicles of therapeutic agents for the treatment of several types of cancer .This article reviews recent articles on studying the role of amni-otic fluid-derived mesenchymal stem cells in cancer therapy .
