The predictive value of plasma TGF-β1 in radiation -induced lung injury for non -small cell lung cancer(NSCLC)
10.3969/j.issn.1002-3070.2014.03.018
- VernacularTitle:血浆 TGF -β1对非小细胞肺癌（NSCLC）放射性肺损伤的预测价值
- Author:
Guangwei LIU
;
Bo HAN
- Publication Type:Journal Article
- Keywords:
TGF-β1;
Non-small cell lung cancer;
Radiation-induced lung injury
- From:
Practical Oncology Journal
2014;(3):276-279
- CountryChina
- Language:Chinese
-
Abstract:
Radiotherapy plays an important role in the treatment of lung cancer .Radiation-induced lung injury is a major complication in the process of radiotherapy .It is of great significance for the treatment and prog-nosis of the diseases to predict the early stage of radiation -induced lung injury in the clinical treatment .TGF-β1(transforming growthfactor-β1) can induce some inflammatory cells including lymphocytes ,neutrophils,mon-ocytes ect,contributing to the formation of fibrosis .Plasma TGF-β1 shows different levels followed different sta-ges of radiation-induced lung injury .This article reviews the value of cytokine TGF -β1 in predicting the radia-tion-induced lung injury over various aspects such as singlely used ,combined with radiation physics and other cytokines,and genomics.
