Research progress in the relationship between insulin like growth factor binding protein-2(IGFBP-2) and lung cancer
10.3969/j.issn.1002-3070.2014.01.015
- VernacularTitle:胰岛素样生长因子结合蛋白-2与肺癌关系的研究进展
- Author:
Suzhen SHAN
;
Feihu YAN
;
Haibo LU
- Publication Type:Journal Article
- Keywords:
Insulin like growth factor binding protein -2;
Lung cancer;
Diagnosis;
Treatment;
Prognosis
- From:
Practical Oncology Journal
2014;(1):71-74
- CountryChina
- Language:Chinese
-
Abstract:
As a high sensitive biomarker of lung cancer ,IGFBP2 plays an important role in the occur-rence,development and treatment of lung cancer .Studies have showed that it promotes tumor progression by acti-vating the IGF1R and integrin mediated signal transduction pathway .Recent researches have demonstrated that it participates in targeted therapy of lung cancer ,which may become a new target for the treatment of lung cancer . This paper makes a review on the relationship between IGFBP 2 and lung cancer .
