The gene expression profile in the pathological diagnosis and differential diagnosis of tumors
10.11904/j.issn.1002-3070.2015.03.019
- VernacularTitle:基因表达谱在肿瘤病理诊断与鉴别诊断中的意义
- Author:
Ruyi LI
;
Jianbo LU
- Publication Type:Journal Article
- Keywords:
Gene expression profiling;
Nasopharyngeal carcinoma;
Lung carcinoma;
Gastric cancer;
Colo-rectal cancer
- From:
Practical Oncology Journal
2015;(3):275-278
- CountryChina
- Language:Chinese
-
Abstract:
Through analyzing the gene expression profile of tumor cells with gene chip technology and se -lecting the differentially expressed genes of different tumor individuals and tumor types ,researchers find that these genes are not only connected with tumor growth ,proliferation,apoptosis,and signal transduction,but also with tumor pathogenesis,tumor infiltration,tumor metastasis and tumor drug resistance .Some tumor differentially ex-pressed genes or genomes show that these genes are even associated with tumor histological source and histological type.It demonstrates practical application value in the pathological diagnosis and differential diagnosis of tumors .