The biology function of Astrocyte elevated gene-1(AEG-1)in hepatocellular carcinoma
10.3969/j.issn.1002-3070.2014.01.013
- VernacularTitle:星形细胞上调基因1(AEG -1)在肝细胞癌中的研究进展
- Author:
Cong LI
;
Jiang LONG
;
Shoupeng SHENG
;
Yu SUN
;
Honghai ZHANG
;
Jianjun LI
;
Jiasheng ZHENG
- Publication Type:Journal Article
- Keywords:
Astrosyte elevated gene 1;
NSL;
Hepatocellular carcinoma;
Hepatitis B virus
- From:
Practical Oncology Journal
2014;(1):61-65
- CountryChina
- Language:Chinese
-
Abstract:
Since initial identification of astrocyte elevated gene -1 ( AEG-1 ) as a HIV-1-inducible novel oncogene in 2002 ,it has emerged as an important oncogene providing a valuable prognostic marker in pa-tients with various cancers.The present review discusses AEG -1 structure,function and localization.Further-more,we summarize the potential role of AEG -1 in the progression of hepatocellular carcinoma (HCC).This re-view can help us better understand the molecular mechanism in hepatocarcinogenesis .