Research progresses of Renin-angiotensin system receptors in breast cancer
10.11904/j.issn.1002-3070.2016.04.014
- VernacularTitle:肾素－血管紧张素系统相关受体在乳腺癌中的研究进展
- Author:
Ting WANG
;
Xuesong CHEN
- Publication Type:Journal Article
- Keywords:
Renin-angiotensin system;
RAS receptor;
Breast cancer
- From:Practical Oncology Journal
2016;30(4):365-369
- CountryChina
- Language:Chinese
-
Abstract:
Recent studies had demonstrated that Renin -angiotensin system ( RAS) plays an important role not only in the cardiovascular system ,but also in the occurrence and development of breast cancer .Associated with RAS receptor ,Angiotensin Ⅱ( Ang Ⅱ) and Angiotensin 1-7 ( Ang1-7 ) which are the major molecules of the RAS,respectively,promote or inhibit the occurrence and development of tumor .In this review,we summarize the current knowledge of the RAS in breast cancer ,and discuss the potential application of RAS related receptors targeted drugs in the clinical treatment of breast cancer .
