The role of apoptosis in pancreatic cancer therapy
10.11904/j.issn.1002-3070.2016.04.016
- VernacularTitle:细胞凋亡在胰腺癌治疗中的作用
- Author:
Xiangxuan ZHAO
;
Feng WEN
;
Zaiming LU
- Publication Type:Journal Article
- Keywords:
Apoptosis;
Pancreatic cancer;
Signal pathway;
Target therapy
- From:
Practical Oncology Journal
2016;30(4):375-379
- CountryChina
- Language:Chinese
-
Abstract:
Pancreatic adenocarcinoma ( PAC) is still a refractory human digest malignancies due to multi-faceted causes ,late diagnosis and insensitive to traditional chemo -and radio-therapy .Resistance to apoptosis could be one of the most relevant mechanisms for PAC to escape any non -surgical therapy .This review aims to clear up the main deregulated apoptosis signal pathways over the years and to find out the abnormal molecule tar -get(s),and therefore,provide novel concepts for PAC molecular targeting therapy .
