Progression in ovarian castration and related treatment
10.3969/j.issn.1002-3070.2014.01.017
- VernacularTitle:乳腺癌药物卵巢去势新进展
- Author:
Weiling SUN
;
Yanbin ZHAO
;
Li CAI
- Publication Type:Journal Article
- Keywords:
Breast cancer;
Medical castration;
Endocrine therapy
- From:
Practical Oncology Journal
2014;(1):81-84
- CountryChina
- Language:Chinese
-
Abstract:
The endocrine therapy of hormone receptor -positive breast cancer has been widely recog-nized.Aromatase inhibitors are better than tamoxifen in efficacy ,tolerability and other aspects .However,AIs is on-ly applied in the menopausal status of breast cancer patients .Therefore,for premenopausal patients with tamoxifen resistance ,the presence of contraindications or the existence of risk factors ,ovarian castration undoubtedly open a gateway to the more and better option for them .Because of the disadvantages of the reversibility, controllability and side effects ,castration surgery and radiotherapy have been gradually replaced by medical castration .In this paper , the new progress are reviewed .Our article aims to make a review on the lastest research on the new progress of breast cancer medical ovariectomized on endocrine therapy ,the comparison with chemotherapy and other aspects .
