The relationship between clincopathological features and prognosis of colorectal cancer in synchronous liver metastases after resection of the primary tumors

VernacularTitle:大肠癌同时性肝转移原发灶切除患者临床病理特征和预后关系分析
Author: Mengxiu ZHU ; Changjie LOU ; Xiaoxue LI ; Haibo LU
Publication Type:Journal Article
Keywords: Colorectal carcinoma; Hepatic metastasis; Clincopathological features; Prognosis
From: Practical Oncology Journal 2015;(4):305-310
CountryChina
Language:Chinese
Abstract: Objective To analyze the clincopathological features and prognosis of 77 colorectal cancer patients with synchronous liver metastases after resection of the primary tumors.Methods Seventy seven colorec-tal cancer patients with synchronous liver metastases who underwent resection of the primary tumors and patholog-ical confirmed were enrolled in this retrospective study.The clincopathological features and prognosis were ana-lyzed.Kaplan-Meier method was used to analyze survival rate.The differences between survival curves were cal-culated by Log-rank test.Results The analysis showed that sex,tumor differentiation and TNM stage were as-sociated with prognosis(P<0.05).The analyses demonstrated no differences in age,primary tumor site,treat-ment,number of liver metastases and extrahepatic metastasis(P>0.05).There was a significant correlation be-tween CEA,CA19-9 level and gender,tumor differentiation and TNM stage(P<0.001)and the corresponding surgical procedure and TNM stage(P<0.05).Conclusion The analysis show that male,the low differentiation and stageⅢare poor prognosis factors.