Research on the progress of the relation between Wnt signaling pathway and the tumorigenesis and pro-gression of non-small-cell lung cancer
10.11904/j.issn.1002-3070.2016.01.014
- VernacularTitle:Wnt信号通路与非小细胞肺癌发生发展关系的研究进展
- Author:
Daquan WANG
- Publication Type:Journal Article
- Keywords:
Wnt signaling pathway;
Non-small-cell lung cancer;
β-catenin;
Tumorigenesis;
Progno-sis
- From:
Practical Oncology Journal
2016;30(1):66-70
- CountryChina
- Language:Chinese
-
Abstract:
Wnt signaling pathway participates in the physiological process of cell growth, differentiation, migration and apoptosis.Its abnormal activation is closely related to the tumorigenesis and progression.Wnt signa-ling is also known to regulate the process of proliferation,angiogenesis,adhesion,invasion and metastasis of tumor cells in non-small-cell lung cancer.There are a lot of members in Wnt signaling pathway and their expression levels affect the prognosis of non-small-cell lung cancer.It plays an instructive role in the individualized treat-ment of non-small-cell-lung cancer to lucubrate the relation between Wnt signaling pathway and the tumori-genesis and progression of non-small-cell lung cancer.
