Primary bone lymphom:report of 7 cases and literature review
10.11904/j.issn.1002-3070.2016.01.008
- VernacularTitle:骨原发性恶性淋巴瘤7例报告及文献复习
- Author:
Mei XUE
;
Jing LIU
;
Ling ZHU
;
Xiaoli ZHENG
;
Li DING
;
Dongmei HAN
;
Hengxiang WANG
- Publication Type:Journal Article
- Keywords:
Bone tumor;
Primary lymphoma of bone;
Diagnosis;
Treatment
- From:
Practical Oncology Journal
2016;30(1):41-43
- CountryChina
- Language:Chinese
-
Abstract:
To explore the clinic characters,treatments and prognosis of patients with primary bone lym-phoma( PLB ) .The clinical symptoms, signs, X -ray features, pathological morphology, immunophenotype and treatment of 7 patients with PLB were analyzed retrospectively and the pertinent literatures were reviewed.The re-sults showed that the main complains of 7 cases of PBL were local pain.The CT showed osteolytic bone destruc-tion and soft tissue swelling.There were 3 cases of diffuse large B cell lymphoma,1 case of Burkitt-type lympho-ma,1 case of periferal T-cell lymphoma,1 case of anaplastic large cell lymphoma,and 1 case of Hodgkins lym-phoma.2 patients presented with stageⅠ,4 with stageⅡ,and 1 with stage 3.The therapeutic procedure includes local radiotherapy combined with chemotherapy and targeted therapy.The clinical presentation of PLB is not spe-cial.The diagnosis and identification of histological type of PLB should be established by histopathological and im-munohistochemistry examinations.Early diagnosis and active therapy could improve the prognosis of PLB.Combi-nation therapy including radiotherapy and chemotherapy is the optimal treatment for PLB.