Advances on correlation between Girdin protein and breast cancer
10.11904/j.issn.1002-3070.2016.01.012
- VernacularTitle:Girdin蛋白与乳腺癌相关性的研究进展
- Author:
Jing ZHOU
- Publication Type:Journal Article
- Keywords:
Girdin;
Breast cancer;
Biomarker
- From:
Practical Oncology Journal
2016;30(1):57-60
- CountryChina
- Language:Chinese
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Abstract:
Girdin protein is a kind of actin binding protein,which has the complex molecular structure and takes part in a variety of signaling pathways related with causing cancer.The biological characteristics of Gir-din protein have close association with the proliferation and invasion of malignant tumor.Recent studies have shown that Girdin protein is closely related with occurrence and progress of breast cancer.Girdin protein expres-sion in breast cancer cells can not only promote the progress of breast cancer,but also affect the lymph node me-tastasis and prognosis.Therefore Girdin protein is expected as an independent biomarker to provide a new direc-tion for breast cancer treatment.