Treatment status and progresses of limited brain metastasis in non-small cell lung cancer
10.3969/j.issn.1002-3070.2014.02.019
- VernacularTitle:非小细胞肺癌局限性脑转移的治疗现状及研究进展
- Author:
Yuefeng HU
;
Xiangying XU
- Publication Type:Journal Article
- Keywords:
Carcinoma;
Non-small-cell lung;
Brain metastasis;
Radiotherapy
- From:Practical Oncology Journal
2014;(2):182-187
- CountryChina
- Language:Chinese
-
Abstract:
The single brain metastases of lung cancer is defined as limited brain metastases .Mechanism of brain metastasis from lung cancer remains to be further studied .Based on surgery ,radiotherapy ,and chemother-apy,the comprehensive treatment on limited brain metastasis of non -small cell lung cancer gets a better result , however ,the indications for combination therapy must be strictly controlled .Increasing radiation doses of local tumor area,followed by whole-brain radiotherapy,can improve tumor local control rate and prolong overall sur-vival.Prophylactic irradiation of whole brain showed no evidence on prolonging the overall survival .For patients with poor general state,targeted drugs combined with whole brain radiotherapy can be tolerated well ,as well as prolonged the overall survival to ertain extent .
