The progress on cell signaling pathways related lung cancer
10.3969/j.issn.1002-3070.2013.06.017
- VernacularTitle:与肺癌密切相关的细胞信号传导通路研究进展
- Author:
Yongfang ZHOU
;
Xiaoli LI
- Publication Type:Journal Article
- Keywords:
Lung cancer;
mTOR;
JAK-STAT;
Notch;
Insulin-like growth factors
- From:
Practical Oncology Journal
2013;(6):563-567
- CountryChina
- Language:Chinese
-
Abstract:
Lung cancer is one of the most common malignant tumors in the world .However,its pathogen-esis is still unclear .With the deep research of related signal pathways underlying the development ,progression and prognosis of lung cancer , we find that the mTOR signaling pathway , JAK-STAT pathway , Notch signaling and IGF have been identified to play a major role in the growth ,proliferation,differentiation,apoptosis and invasion of tumor cells.Therefore this paper is to review the effects of the above several pathways ,which may prove a new ba-sis for the pathogenesis and therapy of lung cancer .
