Sevaral mechanisms of chemoresistance in chondrosarcoma
10.11904/j.issn.1002-3070.2016.02.018
- VernacularTitle:软骨肉瘤化疗耐药机制
- Author:
Jing LUO
;
Ting ZHANG
;
Hui HUANG
;
Dan YANG
- Publication Type:Journal Article
- Keywords:
Chondrosarcoma;
Chemoresistance;
Relative molecular
- From:
Practical Oncology Journal
2016;30(2):176-179
- CountryChina
- Language:Chinese
-
Abstract:
Chondrosarcomas has low morbidity in China,but we should pay more attention to the results it contributed to.Patients usually have poor prognosis because of defect of surgical resection and resistance to con-ventional chemotherapy and radiotherapy.Chemotherapy is a significant method to the chondrosarcoma treatment. If we overcome the difficulty of chemoresistance,chemotherapy will kill the sarcoma cells efficiently and inhibit the capacity of metastasis and invasion.The patients will have better prognosis.Finding the mechanisms of che-moresistance in chondrosarcomas is the key, now we review sevaral recent mechanisms of chemoresistance in chondrosarcoma.
