Research progress of transferrin and transferrin receptor on anti-tumor effect
10.11904/j.issn.1002-3070.2015.01.014
- VernacularTitle:转铁蛋白-转铁蛋白受体抗肿瘤作用研究进展
- Author:
Yueqi CHEN
;
Yimin LIU
;
Dinglin ZHANG
- Publication Type:Journal Article
- Keywords:
Transferrin;
Transferrin receptor;
Anti-tumor;
Progress
- From:
Practical Oncology Journal
2015;(1):65-68
- CountryChina
- Language:Chinese
-
Abstract:
The transferrrin(Tf)and the transferrin receptor(TfR)are effective anti tumor agents which exist widely in human body .The Tf takes an important role in iron metabolism ,while the TfR disturbs iron metab-olism and controls the iron absorbing .The compound of Tf and TfR can induce tumor cells apoptosis .Therefore , the combination of Tf and TfR can inhibit tumor growth efficiently .In addition,it is also good for anti tumor indi-rectly by taking Tf/TfR as target and using artemisinin .This article will review and summarize the anti tumor effect of transferrin and transferrin receptor .
