A Case of CD30 (+)/ALK (-) Systemic Anaplastic Large Cell Lymphoma.
- Author:
Young Do PARK
1
;
Sang Lip CHUNG
;
Kyu Suk LEE
Author Information
1. Department of Dermatology, School of Medicine, Keimyung University, Daegu, Korea. franzes@dsmc.or.kr
- Publication Type:Case Report
- Keywords:
Anaplastic large cell lymphoma;
Anaplastic lymphoma kinase;
CD30(+)
- MeSH:
Aged, 80 and over;
Female;
Humans;
Liver;
Lung;
Lymph Nodes;
Lymphoma, Large-Cell, Anaplastic;
Lymphoma, Non-Hodgkin;
Lymphoproliferative Disorders;
Receptor Protein-Tyrosine Kinases;
Skin;
T-Lymphocytes
- From:Korean Journal of Dermatology
2008;46(3):414-417
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Systemic CD30 positive anaplastic large cell lymphoma (ALCL), a subtype of non-Hodgkin lymphoma (NHL), developes in the internal organs and invades the skin. There have been many cases of primary cutaneous CD30 positive T-cell lymphoproliferative disorder, but reports of systemic ALCL have been rare. We describe herein CD30 positive ALK negative systemic ALCL in a 90-year-old woman with multiple masses and nodules on the skin, lung and liver, as well as enlargement of the hilar and abdominal lymph nodes, of 3 months duration. She died of sudden aggravation of the general condition after 7 days.
