The role of Toll-like receptor 4 in malignant lymphoma
10.11904/j.issn.1002-3070.2014.05.017
- VernacularTitle:Toll 样受体4在恶性淋巴瘤中的作用
- Author:
Li GUO
;
Qingyuan ZHANG
- Publication Type:Journal Article
- Keywords:
Toll-like receptor 4;
Malignant lymphoma;
Pathogenetic mechanism
- From:
Practical Oncology Journal
2014;(5):456-459
- CountryChina
- Language:Chinese
-
Abstract:
The pathogenesis of malignant lymphoma has been an important topic in tumor research ,but it is still unclear.Recent clinical studies showed that the expression level of Toll -like receptor 4(TLR4)was signif-icantly high in mantle cell lymphoma tissue and a variety of lymphoma cell lines .At the same time,the TLR4 ex-pression level was correlated with prognosis .The Role of TLR4 in malignant lymphoma for occurrence and devel-opment is reviewed in this article ,which may elucidate the pathogenesis and provide a new basis for the therapy of lymphoma.
