Research progress in EMT and fibrosis of hepatobiliary system
10.3969/j.issn.1001-5256.2014.07.033
- VernacularTitle:上皮间质转化与肝胆系统纤维化的研究进展
- Author:
Shuaidan ZENG
;
Lei LIU
- Publication Type:Journal Article
- Keywords:
epithelial-mesenchymal transition;
hepatobiliary system;
fibrosis;
reviews
- From:
Journal of Clinical Hepatology
2014;30(7):695-699
- CountryChina
- Language:Chinese
-
Abstract:
Epithelial-mesenchymal transition (EMT),which means the transformation of epithelial cells into mesenchymal cells under the influence of cytokines,leading to pathological changes in tissues.According to recent research findings,EMT plays an important role in or-gan fibrosis.Various types of EMT in the fibrosis of hepatobiliary system,as well as the characteristics of each stage and the disease progres-sion,are described,which is of great significance for understanding the development,termination,and even reversion of EMT and fibrosis of hepatic and biliary epithelial cells.
